MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 4 of 4 15. Non-woody sources are also viable sources of cellulose, although only woody plants and cotton are the main sources for microcrystalline cellulose used as a pharmaceutical excipient. Synergies to simplify formulation challenges and reduce operational costs. Instead, they obtained a stable colloidal suspension. Pharmacel 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. The process is relatively basic; and starts with treating cellulose, obtained as a high-grade pulp obtained from fibrous plant material, with mineral acids, followed by purification and spray-drying. Avicel Microcrystalline Cellulose is a safe and non-hazardous material that is widely used in pharmaceutical formulations and food products (as a bulking agent and to add crispness). 86dXeaAjHe%d*`&>>&_p}=X|_% fTtC aB s!YaxHWtGr"GQ 5S"fMS+_;x@@5 zjrK=;OA:il)b> e ei'wm~oh!=Z@Y:J0#8On`T./iC}^o%7KS"$ rf*Z;JTL-uOHH%%Z,029J_ ( endstream endobj 526 0 obj 465 endobj 527 0 obj << /Filter /FlateDecode /Length 526 0 R >> stream Microcrystalline cellulose (Avicel, FMC Corporation) is prepared by acid hydrolysis of cellulose using 2 M hydrochloric acid at 105 C for 15 min. Catalog Number 102331. stream Buy Chemicals. ECOLOGICAL INFORMATION ECOTOXICITY Practically nontoxic to fish: Rainbow trout LC50 (96hr) > 100%, saturated solution (Microcrystalline cellulose, Avicel PH-101) PERSISTENCE AND BIODEGRADABILITY Inherently biodegradable. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Manufacturer FMC Corporation Product code 103-B Revision date 2014 September 30 Language English. In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. They are made up of sulfated and non-sulfated repeating units of galactose and 3,6-anhydrogalactose. Avicel PH-200 microcrystalline cellulose NF, Ph. However, it yields non-digestible fibre. If breathing is difficult or if . Avicel PC 611 (FMC Biopolymer) Supplied by. : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. 6 XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. Looking for FMC'searnings news? Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. If you are already a ChemPoint customer then sign up for access to our online ordering website. : 160182 Date Approved: 05/25/2010 Revision No. ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM Microcrystalline Cellulose E460 MSDS 1. It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. Report Category. %PDF-1.3 They are white to off-white, free-flowing hydrophilic powders supplied in a variety of viscosity grades corresponding to approximate molecular weight, ranging from 100,000 to 7,000,000 daltons. Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. gwf;J(e0o|1p{R~P^);ao!%{0KD7. . Regulatory Information FMC Corporation: Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations DE102009022738A1 (de) * 2009-05-26: 2010-12-09: J. Rettenmaier & Shne Gmbh + Co. Kg . Remove CAS No. A family of polysaccharide products that allow distinctive drug delivery solutions. The product would later go on to be commercialized under the brand name Avicel by FMC Corporation. X\o^ FMC Corporation. <> 1.3. Accumulation of overhead settled dust may form explosive concentrations in air when disturbed and dispersed. Note that Avicel Microcrystalline cellulose is available in different particle sizes and moisture grades that have different properties and applications. At the same time, its pronounced shear-thinning behavior enables handling of even highly viscous solutions. Microcrystalline Cellulose; Cellulose; Functions. q86@on$^X_HuH;3` High performance lubricant that brings more to the tablet. Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * Home. <> iQuLyI4D@yq#u0dZt=0?QUz{K6by_C"vW~Nj$bo? cas:9000-11-7 msds Carboxymethyl cellulose. vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@ qaj/QU<5OrVMfl{pL? AFFINISOL HPMC HME offers hot melt extrusion process flexibility in choosing a polymer viscosity that optimizes drug release profiles and against the factors affecting solubility. It is widely used within the pharmaceutical, food, and cosmetic sectors as a formulation aid. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. TEXTURECEL is highly purified sodium carboxymethyl cellulose (NaCMC) that forms clear solutions in water at all temperatures, has exceptional water binding properties, and is available in a wide range of viscosity grades. 1 0 obj Product Name Cellulose microcrystalline. We are artists at heart and creators by nature. Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. Trademarks: Avicel PH-102. Date Approved: 05/25/2010. pfTr^i5wOg)y .6 68ZWN hZB{u7ps@uWm 2#@+o/Z {vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ Thus, Avicel contributes no or very few calories to the food system. These co-processed products are designed to solve complex formulation problems, simplify manufacturing processes, and deliver significant cost savings. It is also inert and biocompatible. /Contents 4 0 R endobj {ddn(Y?I#K-}t|l #:FHF'D)/)"{k\pM @LRvdSbi#$yg+\0-U VE-2CZ*K&V.MiLeu86)23NI+6tkLSfmWuR.T\>;8]$ipHJ_)*P.FHyD R^PQ4EC l 4h+:6:]=3?B}Y#eAs(l)V6IOG,OM4'R3#^Op?gYZ; m#6@6O$ ;Ro|U$NSs*\neT &CcB7ysrg7;6Eax $R9+q,)}YK-0/SI0K}d WQC}>e|Gs_Q'+mB| X{URv/Z'` 4w'8sC~ cON&pIk:F/Q&u~.S{"% pg:lfx -. MATERIAL SAFETY DATA SHEET. Avicel Microcrystalline cellulose also serves as a moisture adsorbent and as a general-purpose formulation improver. Superior Performance: Provides excellent water uptake and rapid swelling . FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. Low use levels of GRINDSTED Xanthan Gum are sufficient to provide desired viscosities and textures. Their nomenclature and recommended applications are shown below: Co-processed Avicel grades are high functionality materials designed to bring added performance over and above what standard grades offer. Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. Learn about FMC's differentiated biologically-based crop solutions. HAZARDS IDENTIFICATION EMERGENCY TELEPHONE NUMBERS (302) 451-0100 (FMC Plant - Newark, Delaware) (303) 595-9048 (Medical - U.S. - Call Collect) For leak, fire, spill, or accident emergencies, call: (800) 424-9300 (CHEMTREC - U.S.A. & Canada) (703) 527-3887 (CHEMTREC - Collect - All Other Countries) EMERGENCY OVERVIEW: Off-white, free-flowing, odorless powder. 4 0 obj Request media, explore upcoming events and read our latest updates. Microcrystalline cellulose 9004-34-6 <1 Synonyms are provided in Section 1. Microcrystalline Cellulose / Avicel PH-102. % Copyright 2023 by International Flavors & Fragrances Inc. IFF is a Registered Trademark. . In 1964 FMC, Corporation . lH5JWy}DgKRR"Fs <> Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. % (Microcrystalline Cellulose Market Pr. X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Microcrystalline Cellulose / Avicel PH-102. Standard, 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS . Alginates from IFF are an excellent choice for consistent performance in a variety of applications. From anti-reflux to biomedical implants, alginates are uniquely suited for a wide range of applications. AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. q9;v80q>jZ Avicel Microcrystalline Cellulose: Chemical Identifiers. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. Cellulose microcrystalline. Microcrystalline cellulose (MCC) for industrial purposes is usually obtained from wood pulp and purified cotton linters. Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . !(!0*21/*.-4;K@48G9-.BYBGNPTUT3? SDS. The range of products includes three basic types of carrageenan kappa, iota and lambda from various species of red seaweed. The Microcrystalline Cellulose monograph will be incorporated into and become official with the Second Supplement to . Are you sure you want to delete your template? [FMC Study Number I92-1464]. 102331. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Avicel PC 611 Microcrystalline Cellulose CHEMICAL FAMILY: Carbohydrate, Cellulose Derivative SYNONYMS: Microcrystalline cellulose (INCI name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethylcellulose GENERAL USE: Personal Care MANUFACTURER FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 (General Information) msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Ireland) 2. The short-term limit for total inhalable dust is 20 mg/m3. ;(Imu9Jv_ YhnHTbwP*:mg"T{BO;!QR e,cqO! Description:Chemical PropertiesMicrocrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. In the late 1960s, Avicel Microcrystalline cellulose was registered in the supplement to the National Formulary as a pharmaceutical excipient. "l%I-*j|-)@ EtG[TQd%8,.fg4QqH'-dV ?3Z#GK# dGnF7x*3yY\VUwPhmyYT@f67Zcsmdi!%94K@:L# vJeU-kzRT-(YX/fKC Product and Company Identification . Gloves, eye protection and a dust mask should be used. No. Since cellulose contains both amorphous and crystalline regions, when the crystalline regions are mechanically and chemically isolated and elaborated, various useful ingredients in the form of cellulose crystals are obtained, one of which is Avicel Microcrystalline cellulose. <> Examination of urine, blood and faecal levels of vitamin B 1 during microcrystalline cellulose ingestion showed no difference from control periods (Anonymous, 1966). Are you looking for information about products and services by region? Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& Place an order online, track your orders, download SDS and TDS, and see your quotes, all in one secure place. It is, however, a good source of fibre. Quantity: 1 700 kgs. HMo@9, U Q!R/1*;` Researcher's newest research report, the "Wood Pulp Based Microcrystalline Cellulose Industry Forecast" looks at past sales and reviews total world Wood Pulp Based Microcrystalline Cellulose sales in 2022, providing a comprehensive analysis by region and market sector of . 2 0 obj : 160182. >> They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . It is also used in plaque assays for counting. Molecular weight: Not Applicable 1.5. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. Eur., JPE . . In large quantities it provides dietary bulk and may lead to a laxative effect. Meet our leadership team. \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C PipEAz_xO;`cZsC0qcx;@tp]c*T7ge @Mty?]@SNmpf/]q#I,G1I?SR.@z*Xb KjR hb{T$CQrr Yx%O@~57eL5S\r-|EZ)Y.C]KuIlW]@12KY,S]C"e%b*|YX122igjl; @! ,}b;XQ})+l{~d_=sUtl V"CbKas+;fc>]bt#F,Md]]!5xae ;}rr^NI]rUc^,5Lc(fyyp*a=~U}WveuTLYX/ _V{#* g(*Rrm0gyv9i@0UT:A+{eW/y BS3_!Qv rt^BN! 6 0 obj FIRST AID MEASURES Eye Contact Hold eyes open and rinse slowly and gently with water for 15 to 20 minutes. . Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. This unique functionality can be used in a diversity of applications such as controlled release dosage forms, enteric coatings, microencapsulation and stabilization in solutions and suspensions. However, if handling bulk powders, observance of appropriate safeguards is recommended. 2021 Annual Report. undefined. The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. ( } !1AQa"q2#BR$3br In summary, Avicel microcrystalline cellulose is virtually inert, its energy content is very low or zero and it is not absorbed. Some substance identifiers may have been claimed confidential, or may . Avicel Microcrystalline Cellulose Physical Properties. Explore our commitment to environmental, social, and corporate governance and discover how we are making an impact. This is unlikely to be a problem when Microcrystalline cellulose is consumed as part of a medical product where it is used as an excipient in the formulation. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>> Your file is uploaded and ready to be published. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . ETHOCEL premium ethylcellulose resins are water-insoluble polymers. 1 0 obj gac74 [#B6`Wnw7 This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. P}MFbN#[>r(y Truly distinctive drug delivery solutions. stream Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. Quick Links. Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses CN103842425B . PDF (4.11 mb) Footer menu 1. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . MATERIAL SAFETY DATA SHEET Version: 1.0 1. zW0} kAmS AYiy QJVWwi ED`52u-I~_ViT3+3kIT D2/A5vP5MHt(*vCBZ5UALFS0Mr v6t3dDda!03O$V>S6n| 3Fz. The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. : 1. 8 0 obj Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. Microcrystalline Cellulose. << << Microcrystalline Cellulose (MCC) MSDS 1. Microcrystalline cellulose (C6H10O5)n is refined wood pulp. For this reason, nutritionists regard standard powdered microcrystalline cellulose as having zero energy content. Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. SDS - Safety Data Sheet. The aqueous solution to barrier membrane coating. 1 0 obj (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC Micro Crystalline Cellulose. Burger King, McDonald's and other fast food companies list in the ingredients of several of their foods, microcrystalline cellulose (MCC . A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Avicel Microcrystalline cellulose occurs as a white, odourless, tasteless, fibrous powder composed of porous particles. Learn about our new global sustainability platform, Learn about FMC's industry leading goal of net-zero emissions by 2035, Learn about FMC's differentiated biologically-based crop solutions. Avicel is one of the best-known pharmaceutical excipient brands and, without doubt, one of the most frequently used raw materials in solid oral product formulation and manufacture. stream 9,LL!z The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Manufacturer: FMC BioPolymer. Go to Investor Relations. MATERIAL SAFETY DATA SHEET Avicel PH Microcrystalline Cellulose MSDS Ref. Wu, K. Zuurman, H.W. LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. Magazine: Material safety data sheet - FMC Corporation. Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. By producing Avicel . %PDF-1.4 CAS 9004-34-6, pH 5 - 7.5. Validity Area. MATERIAL SAFETY DATA SHEET. Performing this action will revert the following features to their default settings: Hooray! The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. Revision No. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. Molecular weight: Not Applicable 1.5. The METHOCEL Premium family of water-soluble polymers for pharmaceutical applications offers exceptional flexibility and a broad range of properties typically not found in other water-soluble polymers. JRS Pharma: PROSOLV SMCC 90 LM: Microcrystalline Cellulose, Colloidal Silicon . Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. SCMm_>x^O9l (n. Alubra is also less susceptible to over-blending contributing to more flexible process conditions and reduced waste due to over blended batch failures. It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. CAS 9004-34-6. : 9004-34-6 Date Approved: 01/31/2008 . endobj /PRNewswire/ -- ReportsnReports added Global Microcrystalline Cellulose (MCC) Market Growth 2019-2024 to its online research database. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Microcrystalline Cellulose Side Effects. These include amphiphilicity, a higher degree of crystallinity, surface area, higher hydration properties, and morphology. Product Specifications: Chemical and Physical: Loss on drying, % NMT 6.0* Viscosity, cps, 1.2% solids, 120 sec 39 to 91 . q9;v80 stream As some of the data above show, microcrystalline cellulose possesses unique physicochemical properties that set it apart from native cellulose. Product Name: Microcrystalline Cellulose 1.2. Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. endobj CAS #: 9004-34-6 . Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. l~5C ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? Dyvo5bp#bR W7~IF C" d6zLz~!#>@HO}sx;hm>> 4. Revision No. 4 0 obj Microcrystalline cellulose is a commonly used excipient in the . Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . >z+{!A6wy @nLK3R#hRn sba3;b61V:#Z3X,*?RC!wPmqd7WkA'aZMt6PFV3SEvlY'=p.mn[I{puc\6'ZIyI%rD'zA!"t3I2F ^R;LK,?:&THv*y^K> o0Af?J9J-{s2&cCn)32ADzl%sS5O~J[ Material safety data sheet - FMC Corporation. Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named 'mechanically disintegrated D.P cellulose. Packaging: 34 x 50 kgs fiber drums. (&E. MCC helps in the formation of spheres because of its . 3t;zAXa[j.7ZX[GL9e,>6sVV`T6`#W METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. FMC, JRS and Mingtai were estimated to hold for . All Rights Reserved. United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical.